The coronavirus is killing Black, Hispanic, and American Indian children at much larger numbers than their white peers, according to federal statistics released Tuesday.

The numbers — the most extensive U.S. accounting to date of pediatric diseases and deaths — show there have been 391,814 identified cases and 121 deaths between people under the age of 21 from February to July.

Of those killed by COVID-19, the disease caused by the coronavirus, more than 75 percent have been Black, Hispanic, and American Indian children, even though they represent 41 percent of the U.S. population, according to the Centers for Disease Control and Prevention. The federal agency gathered data from health departments during the country.

The excessive deaths between youths echo pandemic inequalities well-documented among adults. Past researchers have found the virus’s death toll is double as high amongst people of color under age 65 as for White Americans. People of color also disproportionately make up “excess deaths” — those killed by the virus without doing diagnosed or those killed indirectly by the virus’s side effects on the health-care system.

The racial differences among children are in some ways even starker.

Of the children and teens killed, 29 Black, 45 percent were Hispanic, and 4 percent American Indian.

This is the biggest indication yet that there are profound racial differences in children just like there are in adults,” said John Williams, chief of pediatric infectious illnesses at UPMC Children’s Hospital of Pittsburgh. “What that should mean for people is moves like wearing a mask are not just about protecting your family and yourself take sanitization service for your commercial and residential. It is about phylogenic equity.”

One key part could be underlying health inequalities among minority children and young adults.

About 75 percent of those who died had at least one underlying position, and the usual frequent were asthma and obesity — two conditions that disproportionately occur in minority youths.

“On one hand, the small complete number of deaths is reassuring. You’re speaking about hundreds of thousands of children affected, and only 121 killed,” said Frank Esper, a pediatric infectious-disease specialist at Cleveland Clinic Children’s. “At the same time, balances at which minority groups are falling are hard to ignore.”

The CDC report showed to underlying social inequalities that minority children are more disposed to experience than their White peers: crowded living conditions, food, and housing insecurity, parents who are required workers and cannot work from home, wealth and education gaps, and difficulty obtaining health care because of a lack of family resources including insurance, child care, transportation or sick leave.

In the report, CDC officials assume that what’s required is for health departments, medical providers, and communities to “mobilize to eliminate systemic barriers that contribute to health disparities.”

In attachment to social disparities, the racial gap in deaths implies genetic or biologic factors could be at play, said Williams. Some viruses have been given to affect some races more critically. Before a vaccine was produced, for example, pneumococcal meningitis disproportionately harmed Black children, Williams said, even after accounting for social determinants. Then, Haemophilus influenzae type b (also known as Hib) was identified to disproportionately affect Native Americans.

The CDC report indicated that the comparatively low death toll for children was reported when almost all schools were closed and that it is unknown how the reopening of schools could affect those rates.

Tuesday’s CDC report reinforced different prominent characteristics of the virus — that it becomes frequently lethal with age. Between children, only 10 percent of deaths transpired in infants-age 1 or younger. Roughly 20 percent of pediatric claims were between ages 1 and 9. The residual was between ages 10 and 20.

Since the virus began, the way it strikes the aging and leaves the very young relatively unscathed has been a primary and puzzling mystery to scientists. In that regard, the novel coronavirus behaves differently from other viruses, such as seasonal influenza. Those other diseases are particularly dangerous for the very young and very old.

Deciding out why children are less affected, researchers believed, could help them realize how and why the virus sickens and kills other age groups. While there are not yet conclusive answers, developing evidence suggests a key protein — called the ACE2 receptor, which the coronavirus manages to enter cells — is present in a lower cost in the airways of children than in adults.

“Health departments, in collaboration with school districts and the communities they work, can assess and improve health promotion, health access, and health equity for all infants, children, teenagers, and young adults," the agency said. “Finally, health authorities, health providers, and community partners can prepare to remove systemic difficulties that add to health disparities."

What we have to know is there’s the immediate impact of Covid-19 and the indirect impact of all the other services that have been shoved aside during this time," like regular vaccinations and access to medical care, Van Kerkhove said. “So there will be an influence on children as well as exceeding direct disease with this distinct virus, something all of us are genuinely concerned about."